International Academic Journal of Science and Engineering

  • ISSN 2454-3896

Preparation of Bioactive Glass 77S for Bone Tissue Engineering Preparation of Bioactive Glass 77S for Bone Tissue Engineering Preparation of Bioactive Glass 77S for Bone Tissue Engineering Preparation of Bioactive Glass 77S for Bone Tissue Engineering Pre

Hediyeh Nejati Rad and Aliasghar Behnamghader

Abstract: Bioactive glasses are promising alternatives for repairing bone and dental defects due to their merit in enhancing bone regeneration while offering compatibility and non-toxicity. In the current investigation, bioactive glass was synthesized and the effect of thermal treatment was scrutinized on various phases formed in the structure. To this end, the three-component bioactive glass 77S with a composition 77%SiO2-16%CaO-4%P2O5 was chosen and synthesized by sol-gel method. Then, STA and XRD experiments were conducted in order to study the thermal properties and phase behaviour, respectively. The effect of thermal treatment on different phases formed in the sample was assessed at 450, 510, 590, 675 and 740°C that chose by STA analysis. The phase structures of thermally treated samples were evaluated using XRD experiments for all the above mentioned temperatures. Phase analysis results suggested that the synthesized samples had been amorphous while indicating the presence of metastable crystalline phases decomposing by temperature. Moreover, crystalline phases of calcium silicate and calcium phosphate were detected in the structure as the temperature was increased. Surface area of bioactive glass were characterized by BET surface area analysis. Using sol-gel method produces surface areas and pore volumes significantly much higher than glasses obtained by melt, this method presents narrow pore distribution in the mesoscopic scale (2–10 nm)

Keywords: Bioactive glass, bone tissue engineering, sol-gel, thermal treatment

Page: 68-74

Volume 1, Issue 2, 2014